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Stanford's classification further categorizes dissections into those involving the ascending aorta (Type A) or not (Type B) ( Oxidative stress refers to an imbalance between the production of reactive oxygen species (ROS) and endogenous antioxidant defense mechanisms

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Budesonide has 90% first-pass hepatic metabolism, and therefore has less systemic absorption beyond the intestinal tract and the liver, reducing the risk of glucocorticoid toxicity with high doses or long-term use