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The use of nanoparticles such as liposomal -glutathione increase site-specific drug targeting to inflamed tissues, by utilizing the disease state including, enhanced permeability or changes in pH of inflamed tissues

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PGC1α drives NAD biosynthesis linking oxidative metabolism to renal protection [PMID: 26982719] Laboratory literature summary: PGC1α drives NAD biosynthesis linking oxidative metabolism to renal protection