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Activin A was recently found to be associated with muscle loss in cancer models Amyotrophic lateral sclerosis (ALS) a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord Cachexia The loss of body weight and muscle mass that cannot be reversed by eating more food due to a catabolic mechanism Ciliary neurotrophic factor (CNTF) a polypeptide hormone and nerve growth factor primarily found in the nervous system where it promotes neurite outgrowth and collateral axon sprouting Mechano growth factor (MGF), endogenous the IGF-IEc isoform (IGF-IEb in rodent), also called MGF, is produced when skeletal muscles are subjected to stretch or exercise Mechano growth factor (MGF), synthetic A synthetically manufactured peptide corresponding to the 24 most C-terminal residues of IGF-IEc which has been shown to promote cellular proliferation and survival Muscle torque the force generated from a group of muscles, which can be pushing or pulling MyoD a basic helix loop helix (bHLH) transcription factor that belongs to the family of myogenic regulatory factors (MRFs)

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