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Vitamin A deficiency has repercussions on immune functions, such as impaired neutrophil function, suppressing the activity of natural killer (NK) cells, as well as a decline in their number, and damaged capacity of phagocytosing of macrophages

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TNF-α, vascular endothelial growth factor (VEGF), hypoxia-inducible factor, IL-8, angiopoietins) are abundant in the psoriatic skin