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Gizewski, and Michael Knoflach, have nothing to disclose Poster Session I - ACUTE ISCHEMIC STROKE MANAGEMENT 01.00 - ACUTE ISCHEMIC STROKE MANAGEMENT - 01.05 - NEUROINTERVENTION P102 - ESOC25-67 EFFICACY OF GUIDE CATHETER PLACEMENT FOR MECHANICAL THROMBECTOMY IN LARGE VESSEL OCCLUSION STROKE: A SYSTEMATIC REVIEW AND META-ANALYSIS Xin Jiang 1 , Yanbo Li 1 , Jian Guo 1 , Li He 1 1 West China Hospital of Sichuan University, Chengdu, China Background and Aims: The benefit of distal guide catheter placement for mechanical thrombectomy (MT) in large vessel occlusion (LVO) stroke is still indeterminate