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For example, chondrocytes isolated from OA cartilage displayed significant senescence levels, and ABT263 treatment reduced the expression of inflammatory cytokines and promoted cartilage matrix aggregation in OA chondrocytes ( Next, we tested the potential of FOXO4-DRI in removing senescent chondrocytes, which has not been reported before

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This increase may reflect some level of hyperpolarization of the mitochondrial membranes and greater production of ATP, which can be an early sign of severe cellular stress ( Other variables related to photosynthetic efficiency, namely cell density, size and morphology also differed between SS and WT strains