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Teste de independência de vias de sinalização do receptor em modelos genéticos Estudos pré-clínicos utilizaram modelos genéticos de camundongos (incluindo modelos com deleção do receptor β3-adrenérgico) para avaliar se os resultados relacionados ao metabolismo lipídico observados com o AOD9604 são mantidos na ausência de componentes específicos da sinalização adrenérgica

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