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Pretreatment with I3C in a mouse model of myocardial ischemia/reperfusion injury (MIRI) reduced the MIRI-induced infarct size, serum creatine kinase (CK), and lactate dehydrogenase (LDH)
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In another study, it was shown that, under oxidative stress conditions, Ku 70 and Ku 80 were degraded by the activated caspase-3 in the pancreatic acinar cells, whereas S -glutathionylation of procaspase-3 blocked its activation and regulated the activities of Ku indirectly [91]
carnitine (ALC) is the acetyl ester of carnitine