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Thereby, there was a therapeutic resolution of the severe syndromes, including vascular and multiorgan failure otherwise inducing following vessel(s) occlusion (arteries [18,19,20], veins [22,23,24,25,26,27], arteries and veins [28,29,30], peripherally and/or centrally), and other alike procedures [31,32,33,34,35,36,37] and damaging agents [38,39,40,41]
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Third, what would be the ideal timing for potential therapeutic interventions and how should HO-1 responses be assessed, by changes in the level of mRNA, protein, functional activity, or levels of its enzymatic byproducts