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These results combined with the normal initial respiratory burst in the first few minutes following PMA stimulation in Gsr −/− neutrophils (33, 34) strongly suggest that NADPH oxidase assembly, at least in the early phase, is not affected by Gsr deficiency

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Identifying core mechanisms of ASD, such as the excitatory and inhibitory (E/I imbalance) mechanism involving the glutamatergic system, a common perturbation among ASD individuals, can help better understand the etiology of ASD