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[112] investigated whether there was a correlation between C677T polymorphism, birth weight, and the risk of developing CVD in 113 morbidly obese French adolescents (BMI = 39.1 ± 6.4 kg/m 2 ) at the age of 14.4 ± 1.5 years

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28 While studies have identified HBV-related factors associated with increased likelihood of progressing to liver cancer (high viral load, HBeAg positivity, genotype C, and failure to clear HBsAg before the age of 50 29,30 ), there are currently no predictive biomarkers that accurately predict the onset of cancer in the setting of HBV infection